Bio-Techne Expands 3D Stem Cell and Organoid Culture Portfolio with a Fully Defined Synthetic Alternative

Bio-Techne announced the launch of Cultrex™ Synthetic Hydrogel, a fully defined synthetic extracellular matrix (ECM), expanding its established Cultrex™ ECM portfolio and providing researchers with a more reproducible and scalable solution for 3D stem cell and organoid culture workflows.

Cultrex™ Synthetic Hydrogel is designed to reduce lot-to-lot variability commonly associated with traditional biologically derived matrices. By offering a fully defined composition, it enables more consistent experimental conditions across studies and laboratories, improving reproducibility and data reliability in 3D culture systems.

The product supports a broad range of organoid applications, including drug screening, toxicology studies, and personalized medicine research, while reducing reliance on animal-derived matrices and supporting the adoption of New Approach Methodologies (NAMs).

From a regulatory perspective, Cultrex™ Synthetic Hydrogel aligns with FDA initiatives aimed at improving translational predictability by enabling more robust and standardized preclinical models. Its defined composition supports consistency, traceability, and scalability for workflows advancing toward regulatory-facing studies.

Will Geist, President of the Protein Sciences Segment at Bio-Techne, commented:

“This product reflects the evolving needs of researchers as stem cell and organoid models move more quickly from discovery into translational workflows. Cultrex™ Synthetic Hydrogel expands our ECM portfolio with a fully defined, scalable solution that enhances reproducibility and consistency without compromising performance.”

This launch further strengthens Bio-Techne’s comprehensive Cultrex™ portfolio, which includes Basement Membrane Extracts (BME), recombinant proteins, cytokines and growth factors, AI-modified proteins, small molecules, media, and supplements—offering researchers a complete toolbox for 3D culture applications.

As the authorized Bio-Techne distributor in Taiwan, HongJin Co., Ltd. continues to support local researchers with Cultrex™ ECM products and 3D stem cell and organoid culture solutions, providing technical support and application guidance to accelerate research in regenerative medicine, drug discovery, and translational science.