NanoLuc® is a 19 kDa luciferase that delivers over 150-fold brighter luminescence than traditional enzymes with exceptionally low background. It enables high-performance assays including:

• NanoBiT® Technology: A binary system using LgBiT and SmBiT fragments to monitor protein–protein interactions in real time inside live cells.

• HiBiT Tagging: A minimal 11–amino acid tag for sensitive detection of endogenous proteins in live or fixed samples.

• NanoBRET® Assays: Real-time, live-cell measurement of protein interactions and ligand binding via energy transfer between NanoLuc® and fluorescent acceptors.

These technologies empower researchers to interrogate protein expression, stability, localization, and interactions with unmatched clarity.

GloMax® Galaxy: Imaging Designed for NanoLuc®

The GloMax® Galaxy is a user-friendly, benchtop bioluminescent imaging system optimized for NanoLuc® applications. Key features include:

• Multi-Modal Imaging: Capture bioluminescence, fluorescence, BRET, and brightfield images—all in one platform.

• Ultra-Sensitive Detection: Perfect for low-abundance targets and long-term live-cell imaging with minimal phototoxicity.

• Real-Time Monitoring: Observe protein degradation, translocation, and complex formation as they happen.

Together, GloMax® Galaxy and NanoLuc® enable intuitive, high-contrast imaging for even subtle protein dynamics.

Powerful Applications Across Disciplines

Whether you're exploring signaling pathways, validating drug targets, or analyzing gene expression, this dynamic duo supports a broad range of research:

• Drug Discovery – Analyze the effects of compounds on protein interactions and stability.

• Signal Transduction – Visualize intracellular signaling events with precision.

• Gene Expression & Regulation – Quantify transcriptional activity with ultra-low background.

See the Signal. Know the Story.

Combining the bright signal of NanoLuc® with the versatile imaging power of GloMax® Galaxy offers a new frontier in live-cell, real-time protein research. Experience the ease of imaging. Embrace the clarity of data. Illuminate your discovery.

Explore More:

• NanoLuc® Luciferase Technology

• GloMax® Galaxy Bioluminescence Imager