NEURAL REJUVENATION TEAM, ACADEMIA SINICA
Area: MOST Inno Zone
Booth No: N915
Website: https://www.stat.sinica.edu.tw
Exhibitor Profile
🔹 Product Name
Novel Oral ENT1 Inhibitor Small-Molecule Drug
🔹 Indications
Alzheimer’s disease and other neurodegenerative disorders
🔹 Overview
J4 (NRT-001) is an oral small-molecule ENT1 inhibitor designed to restore brain energy metabolism and protect neurons. In AD models, J4 improves cognition, reduces Aβ/tau, and alleviates inflammation and oxidative stress. Preclinical studies are complete. INDs approved in Taiwan and the U.S.; Phase 1 trial is ongoing.
🔹 Team
Formed by experts from Academia Sinica, NTU, and industry, the team excels in CNS drug development and translational research.
Brands
Developing novel therapeutics for Alzheimer’s disease and neurodegenerative disorders
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