Model: Quantum Flex

Category: Cell Therapy and Regenerative Medicine

Exhibitor: TERUMO BLOOD AND CELL TECHNOLOGIES

Booth No: M1101

 

Characteristic

 

Quantum Flex™ is a fully automated, functionally closed cell expansion system designed to support the development, clinical trials, and commercial-scale manufacturing of cell therapies. The system enables the expansion of suspension cells, adherent cells, and extracellular vesicles under low shear conditions. With multiple bioreactor formats available, it offers flexible adaptation to both autologous and allogeneic applications.
Its unique hollow-fiber perfusion technology simulates capillary networks, reducing shear stress during culture and enhancing oxygen transfer rates, thus providing optimal conditions for high-density cell growth. The platform’s advanced software is compliant with current Good Manufacturing Practices (cGMP) and features hierarchical user access control, batch record generation, audit trails, and centralized remote control of multiple units for parallel scale-up operations.
Recently, Terumo BCT developed the Quantum Flex™ 3-in-1 CAR-T Workflow Solution, which significantly improves the efficiency of CAR-T cell production. Compared with traditional methods, this solution offers the following key benefits:
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1. Integrated 3-in-1 Core Workflow:
Eliminates inter-platform transfers, reducing manual open handling time by up to 85%, and significantly enhancing process consistency and stability.
2. Shortened Manufacturing Timeline:
Under serum-free culture conditions, the production cycle is reduced by 28–43% compared to manual processes, effectively lowering cleanroom operational costs.
3. Enhanced Tscm Yield:
Achieves 30% higher yield of Tscm cells compared to manual processes, contributing to potentially improved cell therapy quality.
4. Significantly Improved Viral Transduction Efficiency:
Delivers 2× higher transduction efficiency than manual methods, enabling greater CAR-T cell output while reducing vector usage and overall production costs.

 

 

 

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