Automated Bio-nanoparticle Isolation Platform
Model: NanoEX
Category: Cell Therapy and Regenerative Medicine
Exhibitor: COLD SPRING BIOTECH CORP.
Booth No: L118
Characteristic
Aopia NanoEX™ — Automated Bio-Nanoparticle Purification System
The NanoEX™ system by Aopia is a fully automated platform specifically designed for the isolation and purification of exosome and other biological nanoparticles. Leveraging cutting-edge Asymmetric Nanopore Membrane (ANM) technology, NanoEX™ delivers high purity, excellent recovery rates, and low shear damage. Its fully automated workflow—from sample processing to concentration and collection—is ideal for applications in EV-based drug delivery, cell therapy, and regenerative medicine, offering a reliable, scalable, and efficient solution.
Key Features of NanoEX™:
1. ANM Technology: Engineered with a highly uniform and asymmetric pore structure, ANM enables efficient removal of free proteins while retaining the integrity of EVs. It effectively overcomes membrane clogging issues commonly seen in conventional ultrafiltration (UF) methods.
2. Automated Workflow: End-to-end automation of purification, concentration, and recovery requires less than 5 minutes of hands-on time. Built-in optimized protocols simplify operation and ensure reproducibility across runs.
3. High Purity Performance: Capable of eliminating over 99.99% of free proteins, NanoEX™ ensures high-purity EV preparations while preserving their structural and functional integrity for downstream applications.
4. High Recovery and Scalability: Achieves EV recovery rates exceeding 80% and supports processing volumes from 65 mL to 2 L, accommodating both small-scale research and large-scale manufacturing workflows.
5. Flexible Cassette System: Disposable closed cassettes are ideal for small-volume or clinical samples, minimizing cross-contamination risk. Reusable options are available for large-volume processing, significantly reducing operational costs.
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