Fuji Silysia (ARG / NH-SG Silica) ARG Silica：Arginine Silica NH-SG Silica：Neutral Sugar Grade Silica/ Sugar Grade Amino Silica

Model: ARG Silica 系列： ARG SPS100-5， ARG SMB100-20/45

Booth No: M206

Characteristic

ARG Silica (Arginine Silica) - Designed for HILIC Mode:
Unique Selectivity: Surface-modified with the amino acid arginine, specifically developed for Hydrophilic Interaction Chromatography (HILIC).
Ideal for Highly Hydrophilic Compounds: Exhibits strong affinity and excellent resolution for highly polar compounds that are difficult to retain on traditional reversed-phase (RP) columns, such as peptides, oligopeptides, amino acids, vitamins, and nucleic acid bases.
HILIC Elution Mechanism: In HILIC mode, the elution speed increases as the water content in the mobile phase increases, demonstrating an opposite retention behavior compared to traditional RP chromatography
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NH-SG Silica (Neutral Sugar Grade Silica) - Protecting Precious Sugars:
Overcoming Denaturation Issues: Conventional NH silica has a high pH (approx. 9.0), which can cause sugar denaturation and silica damage under high-water mobile phases. The SG (Sugar Grade) effectively circumvents this problem by featuring a neutral pH of 7.5.
Broad Carbohydrate Purification: Enables stable, safe, and highly efficient separation of monosaccharides, disaccharides, oligosaccharides, and cyclodextrins without unwanted chemical reactions with ketones or carboxyl groups.
Seamless Scale-up Capability: Both materials are available in a comprehensive range of particle sizes from 5 μm to 110 μm, seamlessly supporting scale-up operations from analytical laboratories to pilot and multi-ton industrial preparative purification.