CUBIC Reagents for Animal Tissue, Whole-Organ and Whole-Body Clearing

Model: T3740, T3741 / T3983, T3780

Booth No: M206

Characteristic

The CUBIC technique, developed by Prof. Hiroki R. Ueda and coworkers at The University of Tokyo / RIKEN, is a revolutionary tissue-clearing method.
Ultimate Clearing Efficiency: Achieves whole-organ and whole-body clearing of animal tissues using specific delipidation (CUBIC-L) and refractive index (RI) matching (CUBIC-R+) reagents.
High Fluorescence Preservation: Exhibits remarkably low quenching of fluorescence signals, perfectly preserving fluorescent proteins like GFP.
Section-Free 3D Imaging: Combined with light-sheet fluorescent microscopy (LSFM) or confocal laser-scanning microscopy (CLSM), it enables 3D whole-organ and whole-body imaging at a single-cell resolution without the need for destructive physical sectioning.
Comprehensive Solutions: TCI provides a complete product lineup, including reagents for bone decalcification (CUBIC-B), highly fatty tissue clearing (CUBIC-HL), tissue expansion (CUBIC-X), and 3D immunostaining (CUBIC-HV), meeting diverse and complex imaging demands in biomedical research.