Lingan ─ Multi-channel cell thawing device and Cell Feeder Flask

Category: Cell Therapy and Regenerative Medicine

Booth No: M724

Characteristic

Lingan specializes in the development of process equipment for cell therapy and regenerative medicine, with a strong focus on improving the safety, efficiency, and consistency of cell handling through innovative engineering technologies. From critical cell thawing to expansion culture, the company provides comprehensive solutions tailored to advanced cell manufacturing workflows. Its proprietary water-free porous cell thawing technology achieves cell viability comparable to conventional water bath methods while eliminating the risk of waterborne contamination. The system also fully supports data management, access control, and 3Q validation, making it suitable for GMP and PIC/S manufacturing environments.

Key Features and Advantages
1. Multi-Channel Design for Flexible and Efficient Operation
– Available in 2- and 4-channel models
– Enables simultaneous thawing of multiple cell samples, ideal for parallel processing of large sample volumes while saving time and improving workflow efficiency

2. Water-Free Heating Technology for Reduced Contamination Risk
– Utilizes a dry heat conduction system without the need for water
– Eliminates risks associated with water bath contamination, cross-contamination, and microbial growth, improving sample purity and safety

3. Intelligent Precision Thawing Technology — Designed for Organoids and Small-Volume Samples
– Highly sensitive liquid-level detection supports cryopreservation volumes as low as 0.3 mL
– Targeted heating enables rapid and uniform thawing of organoids
– Users can adjust ice crystal size according to application requirements to enhance cell viability

4. Compliance with 21 CFR Part 11 Electronic Records and Access Control
– Automatically generates PDF reports with per-second data recording and temperature curve display
– Supports hierarchical user access management with three-level permission control
– Fully traceable operation records enhance data integrity and compliance
Designed for seamless integration into GMP and PIC/S manufacturing environments

5. Customizable Modules with Broad Consumable Compatibility
– Modular vial holder design allows rapid customization for different cryovials and containers
– Additional compatible formats can be custom-developed, including AT-Closed Vial, Vial, and CellSeal Cryogenic Vial systems

In addition, the company has developed the Cell Feeder Flask platform, combining the operational convenience of traditional culture flasks with the process advantages of cell bags. This solution is particularly suitable for the expansion and cultivation of immune cells such as T cells, NK cells, and hematopoietic stem cells.

• Unique Gas-Permeable Membrane Design: Features a bottom gas-permeable membrane that provides enhanced oxygen transfer, improving cell culture efficiency.
• Large-Volume Media Capacity: Allows the addition of a large volume of culture medium at one time, eliminating the need for media exchange throughout the process and reducing handling frequency.
• Efficient and User-Friendly: Optimized workflow design enhances operational convenience and improves production efficiency.
• Recommended Cell Seeding Density: 8 × 10⁷ – 1 × 10⁸ cells.